The Typical High Pressure liquid chromatography system configuration contains Solvent cabinet, degasser, pump, autosampler, column compartment and detector. HPLC is a basic detector which help to separate the compounds and detects. The deferent detectors are VWD, DAD,MWD, RID, FLD, ELSD etc and helps for qual and quant analysis. HPLC system are used as front end
Mass spectrometer is a detector which sort ions based on their mass-to-charge ratios (m/z) in vacuum. The quadrupole is the most widely used analyzer having good linearity for quantitative analysis, mass range coverage, good resolution and quality of mass spectra. It’s composed of two pair of rods, one set of rods works on positive potential